Follow the latest developments from Turmesac® and Star Hi Herbs, including peer-reviewed publications, scientific research updates, product announcements and educational articles for nutraceutical formulators.
Turmesac® is a synergistic phytochemical composition derived from turmeric rhizome. Its research portfolio includes 12 preclinical studies across in-vitro and in-vivo models and six international publications covering anti-inflammatory, hepatoprotective, antioxidant, bioavailability and anticancer potential.
Star Hi Herbs has developed a growing body of scientific evidence for Turmesac®, including studies involving cellular, biochemical and animal models. The research evaluates areas such as inflammation, oxidative stress, liver protection and cellular health.
Published in the International Journal of Pharmacy and Pharmaceutical Sciences, this study evaluated Turmesac® in HepG2 human liver cells and RAW 264.7 macrophages. At the selected concentration of 50 µg/ml, Turmesac® reduced intracellular oxidative-stress signals and suppressed the expression of the pro-inflammatory cytokines IL-8 and IL-12 in the study models.
Published in the European Journal of Biomedical and Pharmaceutical Sciences, the study evaluated Turmesac® at 250 and 500 mg/kg in croton-oil-induced ear edema and histamine-induced paw edema models. The researchers reported dose-dependent anti-inflammatory activity, including 58.65% edema inhibition at two hours in the high-dose croton-oil model.
A study published in the Asian Journal of Pharmaceutical and Clinical Research evaluated Turmesac® in HeLa cells. The reported IC50 was 115.12 µg/ml, with apoptosis induction and changes in cell-cycle distribution observed under the experimental conditions. The authors stated that additional research would be required before clinical application could be considered.
This in-vivo study assessed Turmesac® at 250 and 500 mg/kg in a paracetamol-induced hepatotoxicity model. The researchers reported improvements in liver-related biochemical markers, antioxidant enzymes and liver-tissue architecture compared with the toxic-control group.
Published in the Journal of Medicinal Plants Research, this study examined Turmesac® using HUH-7 human liver cells, MCF-7 breast cancer cells and a DPPH antioxidant assay. The findings included dose-dependent protection against hydrogen-peroxide-induced stress and measurable free-radical-scavenging activity.
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The findings discussed on this page are based primarily on preclinical in-vitro and in-vivo research. They do not establish clinical efficacy in humans. Turmesac® is not intended to diagnose, treat, cure or prevent any disease.
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